The PIN1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to DOD. This antibody recognizes Human, Mouse, and Rat antigen. The PIN1 Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Pin1, a member of the parvulin family of peptidyl-prolyl isomerases (PPIase), has been implicated in the G2/M transition of the mammalian cell cycle (1-6). Pin1 is a small (18 kDa) protein with two distinct functional domains: an amino-terminal WW domain and a carboxy-terminal PPlase domain. Pin1 interacts with several mitotic phosphoproteins, including Plk1, cdc25C and cdc27, and is thought to act as a phosphorylation-dependent PPlase for these target molecules (7-9)